• The Stem Company Regenerative Serum 30ml bottle on a white background
  • Woman applying ReGenerative Serum to her cheek
  • ReGenerative Serum
    ReGenerative Serum
  • ReGenerative Serum
    ReGenerative Serum
  • ReGenerative Serum
    ReGenerative Serum
  • ReGenerative Serum
    ReGenerative Serum
  • ReGenerative Serum 30 mL bottle and carton
  • Key ingredients in ReGenerative Serum: Consortia Factors, superoxide dismutase, and sodium hyaluronate
  • ReGenerative Serum eight-week study results and before-and-after photos
  • How to apply ReGenerative Serum morning and evening to the face, under eyes, neck, and décolleté
  • Side-profile comparison before and after eight weeks of ReGenerative Serum use
  • Front-view comparison before and after eight weeks of ReGenerative Serum use
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ReGenerative Serum

Plant Stem Cell Serum for Face, Under-Eyes, Neck & Décolleté

Patented technology. Clinically studied.

Over 90% bioactive ingredients, including peptides, plant-derived exosomes and patented Consortia Factors®.

$150.00
$150.00
    Key Benefits
    • Over 90% bioactive ingredients with patented Consortia Factors®
    • In an independent 8-week study, 82.9% reported smoother skin and 82.9% reported firmer skin
    • One serum for face, under-eyes, neck and décolleté
    • Developed by Dr. Nathan Newman, MD, board-certified dermatologist and founder of The Stem Company
    • No adverse events reported during the independent 8-week study
    Product details
    Targets
    Fine lines · uneven tone · texture · firmness
    Suited for
    Contains fragrance; individual tolerance varies. See the FAQ.
    Format
    Lightweight, water-based serum
    Key ingredients
    Consortia Factors® (with plant exosomes, peptides & metabolites) · Superoxide Dismutase · Hyaluronic Acid
    The Stem Company Regenerative Serum 30ml bottle on a white background
    Woman applying ReGenerative Serum to her cheek
    ReGenerative Serum ReGenerative Serum ReGenerative Serum ReGenerative Serum
    ReGenerative Serum 30 mL bottle and carton
    Key ingredients in ReGenerative Serum: Consortia Factors, superoxide dismutase, and sodium hyaluronate
    ReGenerative Serum eight-week study results and before-and-after photos
    How to apply ReGenerative Serum morning and evening to the face, under eyes, neck, and décolleté
    Side-profile comparison before and after eight weeks of ReGenerative Serum use
    Front-view comparison before and after eight weeks of ReGenerative Serum use
    Why it works
    • 82.9%reported smoother skin
    • 82.9%reported firmer skin
    • 82.9%reported more radiant skin

    Independent 8-week study of ReGenerative Serum used twice daily by 35 women aged 48–70 (mean age 62.8). Participant-reported questionnaire results. Single-arm, open-label study. Individual results may vary.

    • 90%+ bioactive
    • Paraben-free
    • Sulfate-free
    • Phthalate-free
    • Silicone-free
    • No drying alcohols
    • Non-comedogenic
    • Cruelty-free
    • Vegan
    What it is

    ReGenerative Serum is a dermatologist-developed formula for hydrated, smoother-looking skin, with over 90% bioactive ingredients.

    Consortia Factors® is a patented complex produced by growing yeast together with plant stem cells. The active material is the metabolites, peptides, lipids and plant-derived exosomes these cultured cells produce. The cells are not alive in the finished formula.

    In an independent 8-week study of ReGenerative Serum, 35 women aged 48–70 (mean age 62.8) used the serum twice daily. At week 8, 82.9% reported smoother skin, 82.9% reported firmer skin and 82.9% reported more radiant skin. 79% of participants showed lighter age spots in 8 weeks, measured by independent image analysis. No adverse events were reported during the study.

    Single-arm, open-label study without a control group. Questionnaire results are participant-reported. Individual results may vary. Results apply to ReGenerative Serum only.

    Read the published study record.

    What makes it different

    • Over 90% bioactive ingredients

      The formula contains UCFx-F™ Consortia Factors®, plant-derived exosomes, peptides, superoxide dismutase and sodium hyaluronate.

    • Patented plant stem cell technology

      Consortia Factors® is a patented complex produced by growing yeast together with plant stem cells. The active material is the metabolites, peptides, lipids and plant-derived exosomes these cultured cells produce. The cells are not alive in the finished formula. US Patents 11,473,117 and 12,569,537.

    • Clinically studied on mature skin

      In an independent 8-week study of ReGenerative Serum, 35 women aged 48–70 (mean age 62.8) used the serum twice daily. At week 8, 82.9% reported smoother skin, 82.9% reported firmer skin and 82.9% reported more radiant skin. 79% of participants showed lighter age spots in 8 weeks, measured by independent image analysis. No adverse events were reported during the study.

    Key ingredients

    • Consortia Factors® (UCFx-F™)

      Consortia Factors® is a patented complex produced by growing yeast together with plant stem cells. The active material is the metabolites, peptides, lipids and plant-derived exosomes these cultured cells produce. The cells are not alive in the finished formula.

      Plant-derived bioactives for smoother-looking skin.

    • Superoxide Dismutase (SOD)

      An antioxidant enzyme that helps defend skin against free radicals.

      Antioxidant support for your daily skincare routine.

    • Sodium Hyaluronate

      A form of hyaluronic acid that helps attract and retain moisture.

      Helps skin feel hydrated and look plumper.

    How to use

    Step 2 of every ritual — the core signal.

    Smooth 1–2 pumps across clean skin including face, under eyes, neck and décolleté. Massage in upward circular motions until fully absorbed. Morning and evening.

    What to Expect
    TimeframeWhat you may notice
    Daily use Apply morning and evening according to the product directions.
    8 weeks In an independent study, 82.9% reported smoother skin, 82.9% firmer skin and 82.9% more radiant skin.
    Individual results Results vary. The study was single-arm and open-label, with 35 women aged 48–70.

    Full Ingredient List (INCI)

    Water, Glycoproteins, Glycerin, Ustilago Cynodontis Ferment (UCFx-F™), Hydroxyethylcellulose, Gluconolactone, Mineral Salts, Xanthan Gum, Sodium Benzoate, Soy Amino Acids, Sodium Hydroxide, Allantoin, Panthenol, Sodium PCA, Sodium Hyaluronate, Superoxide Dismutase, Caprylyl/Capryl Glucoside, Sodium Cocoyl Glutamate, Glyceryl Caprylate, Citric Acid, Polyglyceryl-6 Oleate, Sodium Surfactin, Fragrance.

    Formulated without parabens, sulfates, phthalates, drying alcohols, and silicones. (Plant exosomes, peptides, and metabolites occur naturally within the Consortia Factors® / Ustilago Cynodontis Ferment complex.)

    FAQ

    What makes ReGenerative Serum distinctive?

    Over 90% of the formula is bioactive, with patented Consortia Factors®. One serum is designed for the face, under-eyes, neck and décolleté.

    Are the plant stem cells alive in the serum?

    Consortia Factors® is a patented complex produced by growing yeast together with plant stem cells. The active material is the metabolites, peptides, lipids and plant-derived exosomes these cultured cells produce. The cells are not alive in the finished formula.

    What did the clinical study evaluate?

    In an independent 8-week study of ReGenerative Serum, 35 women aged 48–70 (mean age 62.8) used the serum twice daily. At week 8, 82.9% reported smoother skin, 82.9% reported firmer skin and 82.9% reported more radiant skin. 79% of participants showed lighter age spots in 8 weeks, measured by independent image analysis. No adverse events were reported during the study. Single-arm, open-label study without a control group. Questionnaire results are participant-reported. Individual results may vary. Results apply to ReGenerative Serum only.

    Does ReGenerative Serum contain fragrance?

    ReGenerative Serum contains fragrance. Individual sensitivities vary, so the formula may not suit everyone who is sensitive to fragrance. Patch-test before full use. No adverse events were reported in the independent 8-week study; this does not guarantee that every user will tolerate the formula.

    Complete the ritual

    • RePure Cleanser

      RePure Cleanser

      $42.00

      Step 1 — morning and night, in every ritual.

    • ReNew Moisturizer

      ReNew Moisturizer

      $85.00

      Step 3 (daytime) of the 3-Step Renewal Ritual. Pairs with ReVitalize Cream at night.

    • ReVitalize Cream

      ReVitalize Cream

      $90.00

      Step 3 (night) of the 3-Step Revitalize Ritual. Can be used day and night in dry climates.