Science-Backed, Ethically Made
At The Stem Company, we believe being free from potentially harmful ingredients should be the bare minimum for personal care products.
We fuse scientific research with biointelligent plant-based ingredients to create formulas that deliver measurable change without compromising your health or the planet. We own every step of the process to ensure what’s on your skin reflects what’s behind the scenes: sophistication and integrity.

THE SECRET BEHIND STEM CELL SKINCARE
Utilizing patented platform technology at Rinati Labs, The Stem Company cultivates its proprietary Consortia Factors® (CFx®) by growing yeast together with plant stem cells.
The resulting CFx® complex contains the unadulterated bioactive secretome produced by these cultured cells, including metabolites, peptides, lipids, and plant stem cell-derived exosomes. Together, these naturally produced compounds form a sophisticated, multi-pathway biological signaling system designed to support skin renewal and rejuvenation.
THE PATENT
Our Consortia Factors® Technology
Consortia Factors® is a patented complex produced by growing yeast together with plant stem cells. The active material is the metabolites, peptides, lipids and plant-derived exosomes these cultured cells produce. The cells are not alive in the finished formula.
US Patents 11,473,117 and 12,569,537.

Consortia Factors® is a patented complex produced by growing yeast together with plant stem cells. The active material is the metabolites, peptides, lipids and plant-derived exosomes these cultured cells produce. The cells are not alive in the finished formula.
Different formulas use plant partners including flax, tulsi, hibiscus and shikakai. These bioactive compounds are formulated with other skincare ingredients to support hydration and smoother-looking skin.
Dr. Newman is co-founder and chair of Rinati Skin LLC, the research and manufacturing company that holds the Consortia Factors® patents and produces The Stem Company's formulas.
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FAQs
Does The Stem Company use human stem cells?
No. The Stem Company’s skincare does not contain living human or plant stem cells. Consortia Factors® is a patented complex produced by growing yeast together with plant stem cells. The active material is the metabolites, peptides, lipids and plant-derived exosomes these cultured cells produce. The cells are not alive in the finished formula.
How do stem cells help with skincare?
Plant stem cell technology provides bioactive compounds produced during cell culture. The Stem Company formulates these compounds into products that help hydrate skin and improve its visible texture and radiance.
What types of concerns does The Stem Company help with?
Our advanced, multitasking formulas are designed to address a wide range of visible skin concerns across all skin types. Whether you’re looking to maintain youthful radiance or reduce the look of past damage, STEM can help with:
- Fine lines & wrinkles – by supporting natural collagen and helping improve elasticity.
- Uneven skin tone – by visibly reducing hyperpigmentation, sun spots, and dark marks.
- Dryness & dehydration – by replenishing hydration and reinforcing the moisture barrier.
- Dullness – by restoring luminosity and a more radiant appearance.
- Loss of firmness – by helping skin look lifted and more resilient with bioactive peptides.
- Blemish-prone skin – by calming the look of irritation and supporting a balanced skin environment.
Sensitive or reactive skin – by soothing visible redness and discomfort without harsh ingredients.
Are plant stem cells really effective for anti-aging?
The relevant clinical evidence is specific to the finished ReGenerative Serum formula.
In an independent 8-week study of ReGenerative Serum, 35 women aged 48–70 (mean age 62.8) used the serum twice daily. At week 8, 82.9% reported smoother skin, 82.9% reported firmer skin and 82.9% reported more radiant skin. No adverse events were reported during the study.
Single-arm, open-label study without a control group. Questionnaire results are participant-reported. Individual results may vary. Results apply to ReGenerative Serum only.


