THE SCIENCE OF STEM
A patented bioactive complex grown by co-culturing two living systems — so skin receives a richer, more intelligent signal than any single source can give, helping it revive, renew, and remember its youthful behavior.
UCFx-F™ · U.S. Patent 11,473,117 B2
HOW IT WORKS
Most ferment and growth-factor serums use the output of a single cell type. Consortia Factors® co-cultures a yeast (Ustilago cynodontis) with different types of plant stem cells, such as flax, hibiscus, and tulsi. Grown together, the two communicate and produce a combined secretome — metabolites, peptides, lipids, and plant-derived exosomes — that neither makes alone.
Two living systems, one richer source.
Yeast and plant stem cells are grown together, producing a combined secretome of metabolites, peptides, lipids, and plant-derived exosomes. About one-third of its beneficial metabolites are unique to the pairing.
Speaks your skin's language.
Its consortia exosomes, peptides, and signaling metabolites carry renewal messages between cells, helping activate the skin's own renewal pathways, while skin-mimetic lipids reinforce the barrier.
Across multiple pathways, not one.
Enriched antioxidant and anti-inflammatory metabolites neutralize free radicals and reduce intracellular processes that drive visible aging, while the complex helps retrain skin toward firmer, more even-toned, youthful behavior over time.
In published research, Consortia Factors® showed stronger antioxidant and anti-inflammatory activity on human dermal cells than conventional cultures.
| Source | Relative antioxidant / anti-inflammatory activity |
|---|---|
| Yeast alone | Low |
| Tulsi alone | Low |
| The two combined | Moderate |
| Consortia Factors® | Highest |
Reference: Zemach A, Plaza MR, Simmons D, et al. "Yeast–Plant-Derived Consortia Factors Exhibit a Distinct and Enriched Beneficial Metabolome for Health and Beauty." bioRxiv, 2026.