What Are Consortia Factors®?
For years, skincare has focused on surface-level results: exfoliating, moisturizing, resurfacing, brightening. But true renewal doesn’t happen on the surface. It happens at the level of cellular communication, and that is where Consortia Factors® change everything.
At the core of The Stem Company’s formulas is Consortia Factors® technology, a proprietary bio-intelligent system developed by regenerative medicine specialist Dr. Nathan Newman. Instead of treating symptoms, Consortia Factors® activate the skin’s own ability to repair, rebuild, and regenerate — the same way it did when it was younger.
This is not another ingredient trend. It is a biological language.
What Exactly Are Consortia Factors® made up of?
Consortia Factors® (CFx) are complete sets of rejuvenating signals created in a controlled lab environment. They are not single actives, extracts, or synthetic additives. They are multi-layered messengers designed to mimic the body’s natural communication system for healing and renewal.
Each CFx set includes:
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Secretory Factors
Bioactive messengers that trigger cellular repair -
Exosomes
Nano-vesicles that deliver growth and repair signals -
Natural Peptides
Support collagen production and structural rebuilding -
Beneficial Metabolites
Nourish, stabilize, and protect the skin environment -
Sigmasomes
Advanced delivery carriers for deeper, targeted absorption
Traditional skincare gives the skin a single ingredient and hopes for a reaction.
Consortia Factors® deliver complete regenerative instruction.
How They Are Created
The technology is built on plant-based stem cell bio-communication, cultivated in Dr. Newman’s lab using a patented Cell-to-Bottle™ process. This process stabilizes the full signaling set and preserves it in its complete form, ensuring purity, potency, and repeatable results.
This makes CFx fundamentally different from:
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“Stem cell–inspired” marketing claims
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Skincare built on extracts or isolated actives
Retinol or acid systems that rely on irritation to create change
Consortia Factors® do not force the skin to react.
They remind it how to function.
Why This Matters More Than Traditional Actives
Most skincare ingredients treat symptoms at the surface.
Consortia Factors® restore the system beneath it.
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They work with the skin, not against its biology
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They activate repair instead of causing controlled injury
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They address the source of aging, loss of cellular instruction
Results aren’t temporary; they are process-driven and accumulative
This is not anti-aging.
This is pro-regeneration.
The Science Behind the Breakthrough
Dr. Newman explains it simply:
“Skin doesn’t stop renewing because it loses the ability. It stops because it no longer receives the right signals. Consortia Factors® restore that communication.”
This is the same science used in tissue repair and regenerative medicine, now applied to daily skincare for visible renewal.
What This Means for the Future of Skincare
The next era of skincare won’t be defined by stronger acids or higher percentages. It will be defined by precision biology, cellular signaling, and intelligent restoration.
Consortia Factors® mark the shift from ingredients that act on the skin
to signals that act with it.
Explore the science in action
The ReGenerative Serum is the first serum powered by full Consortia Factors® Technology.


